Endocrine Abstracts

Background: Thyroid dysfunctions are among the most common immune-related adverse events (irAEs) following the administration of immune checkpoint inhibitors (ICIs) for malignancies. The pathogenesis of thyroid irAEs remains unclear and the clinical course can be multifaceted.Aim: Aims of this study were a) to describe the incidence and the clinical course of thyroid irAEs b) to determine the association between thyroid irAEs and overall survival (OS).</...

About 5–10% of fertile women have anti-thyroid antibodies (AAT); however this prevalence is higher in infertile women. Few studies have been focused so far on the role of thyroid autoimmunity in the outcome of ART. Aims of our studies have therefore been: a) evaluate prevalence of thyroid antibodies in infertile women before ART; b) investigate whether AAT are more prevalent in a specific subset of infertile women; c) investigate the possible influence of AAT or thyroid d...